Human Analogue of the Morris Water Maze for Testing Subjects at Risk of Alzheimer’s Disease

0342081 - FGÚ 2011 RIV CH eng J - Článek v odborném periodiku
Laczó, J. - Andel, R. - Vyhnálek, M. - Vlček, Kamil - Magerová, H. - Varjassyova, A. - Tolar, M. - Hort, J.
Human Analogue of the Morris Water Maze for Testing Subjects at Risk of Alzheimer’s Disease.
Neurodegenerative Diseases. Roč. 7, 1-3 (2010), s. 148-152. ISSN 1660-2854. E-ISSN 1660-2862
Grant CEP: GA ČR(CZ) GA309/09/1053; GA ČR(CZ) GA309/09/0286
Výzkumný záměr: CEZ:AV0Z50110509
Klíčová slova: mild cognitive impairment * spatial navigation * Alzheimer’s Disease
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 3.791, rok: 2010

Alzheimer’s disease is from its start associated with a loss of spatial navigation. The study describes our results from the assessment of spatial navigation abilities in several subgroups of mild cognitive impairment (MCI). Impaired in these spatial abilities were patients diagnosed with amnestic MCI, especially of hippocampal type and patients with ApoE4+ phenotype, connected with a higher risk of progression to Alzheimer’s disease
Trvalý link: http://hdl.handle.net/11104/0184908