Pyranose dehydrogenases: biochemical features and perspectives of technological applications

0339249 - MBÚ 2010 RIV DE eng J - Článek v odborném periodiku
Peterbauer, C. - Volc, Jindřich
Pyranose dehydrogenases: biochemical features and perspectives of technological applications.
Applied Microbiology and Biotechnology. Roč. 85, č. 4 (2010), s. 837-848. ISSN 0175-7598. E-ISSN 1432-0614
Výzkumný záměr: CEZ:AV0Z50200510
Klíčová slova: Pyranose dehydrogenase * Sugar oxidoreductase * Regioselectivity
Kód oboru RIV: EE - Mikrobiologie, virologie
Impakt faktor: 3.280, rok: 2010

Pyranose dehydrogenase is a fungal flavin-dependent sugar oxidoreductase which is structurally and catalytically related to fungal pyranose oxidase and cellobiose dehydrogenase, and probably fulfils similar biological functions in lignocellulose breakdown. It is a monomeric secretory glycoprotein and is limited to a rather small group of litter-decomposing basidiomycetes. Compared to pyranose oxidase it displays a broader substrate specificity and a variable regioselectivity, and is unable to utilize oxygen as electron acceptor, using substituted benzoquinones and (organo)metallic ions instead. Depending on the structure of the sugar in pyranose form (mono-/di-/oligo-saccharide or glycoside) and the enzyme source, selective monooxidations at C-1, C-2, C-3 or dioxidations at C-2,3 or C-3,4 of the molecule to the corresponding aldonolactones (C-1), or (di)dehydrosugars (aldos(di)uloses) can be performed
Trvalý link: http://hdl.handle.net/11104/0182831