A novel ATP-binding cassette transporter is responsible for resistance to viologen herbicides in the cyanobacterium Synechocystis sp. PCC 6803

0334652 - MBÚ 2010 RIV GB eng J - Článek v odborném periodiku
Prosecká, J. - Orlov, V. N. - Fantin, Y. S. - Zinchenko, V. V. - Babykin, M. M. - Tichý, Martin
A novel ATP-binding cassette transporter is responsible for resistance to viologen herbicides in the cyanobacterium Synechocystis sp. PCC 6803.
FEBS Journal. Roč. 276, č. 15 (2009), s. 4001-4011. ISSN 1742-464X. E-ISSN 1742-4658
Grant CEP: GA MŠMT ME 881
Výzkumný záměr: CEZ:AV0Z50200510
Klíčová slova: ABC-type transporter * cyanobacteria * oxidative stress
Kód oboru RIV: EE - Mikrobiologie, virologie
Impakt faktor: 3.042, rok: 2009

Viologens generate reactive oxygen species in photosynthetic cells. Three independent methyl viologen-resistant spontaneous mutants of Synechocystis sp. PCC 6803 were identified, in which the conserved residue of the Slr1174 was mutated.. The Slr1174 protein of the DUF990 family is related to the permease subunit of an ABC-2-type transporter . Our data suggest that Slr1901, Slr1174 and Slr0610 form a heteromeric ATP-binding cassette-type viologen exporter, in which each component is critical for viologen extrusion
Trvalý link: http://hdl.handle.net/11104/0179332