0211581 - UT-L 20000217 RIV CZ eng C - Konferenční příspěvek (zahraniční konf.)
Brožková, K. - Pásek, Michal
Computer modelling of origin of arrhythmias in myocardial cell.
Engineering mechanics 2000. Vol. 3. Praha: UTAM AV ČR, 2000 - (Náprstek, J.; Minster, J.), s. 77-82. ISBN 80-86246-06-X.
[International conference Engineering mechanics 2000. Svratka (CZ), 15.05.2000-18.05.2000]
Grant ostatní: ÚT AV ČR(XC) PP 20/7U
Výzkumný záměr: CEZ:AV0Z2076919
Klíčová slova: quantitative modelling * arrhythmias * carrdiac cell
Kód oboru RIV: BO - Biofyzika

This contribution presents the effect of changes of membrane channel conductivity on the origin of arrhythmias in cardiac cells. The simulations were performed for stimulation frequency 2Hz and compared with results for stimulation frequency 1Hz. It was confirmed that the increase of conductivity of ICa-channels and decrease of conductivity of IK1, INaCa and INaK channels induce single cell arrhythmias.
Trvalý link: http://hdl.handle.net/11104/0107130