New 2-alkynyl derivatives of the acyclic nucleoside 9-(2,3-dihydroxypropyl)adenine and their 6-guanidinopurine counterparts as potential effectors of adenosine receptors

0194994 - UOCHB-X 20030302 RIV CZ eng J - Článek v odborném periodiku
Česnek, Michal - Holý, Antonín - Masojídková, Milena
New 2-alkynyl derivatives of the acyclic nucleoside 9-(2,3-dihydroxypropyl)adenine and their 6-guanidinopurine counterparts as potential effectors of adenosine receptors.
Collection of Czechoslovak Chemical Communications. Roč. 68, č. 11 (2003), s. 2201-2218. ISSN 0010-0765
Grant CEP: GA AV ČR IBS4055109; GA MŠMT OC D13.20
Výzkumný záměr: CEZ:AV0Z4055905
Klíčová slova: adenosine receptors * alkynes * purines
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 1.041, rok: 2003

A series of the new 2-alkynyl derivatives of the acyclic nucleoside 9-(2,3-dihydroxypropyl)-adenine and their 6-guanidinopurine analogues were prepared by the Sonogashira coupling. The effect of the prepared compounds on A₁ and A_2A receptors was examined.
Trvalý link: http://hdl.handle.net/11104/0090664