0194917 - UOCHB-X 20030225 RIV US eng J - Článek v odborném periodiku
Králíková, Šárka - Buděšínský, Miloš - Rosenberg, Ivan
ŕ-Hydroxyphosphonate oligonucleotides: A promising DNA type?
Nucleosides Nucleotides & Nucleic Acids. Roč. 22, 5/8 (2003), s. 1061-1064. ISSN 1525-7770. E-ISSN 1532-2335.
[International Roundtable Nucleosides, Nucleotides and Nucleic Acids /15./. Leuven, 10.09.2002-14.09.2002]
Grant CEP: GA ČR GA203/01/1166; GA AV ČR IAA4055101
Výzkumný záměr: CEZ:AV0Z4055905
Klíčová slova: isopolar phosphonate oligonucleotides * nucleoside 5'-phosphonic acids * phosphotriester method
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 0.813, rok: 2003

The synthesis of monomers (.I.S./I.)-1, (.I.R./I.)-1 and 2 derived from (5'.I.S./I.)-, (5'.I.R./I.)-2'-deoxy-thymidine-5'-.I.C./I.-phosphonic acids and 2',5'-dideoxythymidine-5'-.I.C./I.-phosphonic acid was elaborated. The protection of the 5'-hydroxyl by the methoxycarbonyl group was a key step of the synthesis.
Trvalý link: http://hdl.handle.net/11104/0090587