Počet záznamů: 1
Study on reactivity and protection of the ŕ-hydroxyphosphonate Moiety in 5'-nucleotide analogues: formation of the 3'-O-P-C(OH)-C4' internucleotide linkage
- 1.0194810 - UOCHB-X 20030116 RIV US eng J - Článek v odborném periodiku
Králíková, Šárka - Masojídková, Milena - Buděšínský, Miloš - Rosenberg, Ivan
Study on reactivity and protection of the ŕ-hydroxyphosphonate Moiety in 5'-nucleotide analogues: formation of the 3'-O-P-C(OH)-C4' internucleotide linkage.
Nucleosides Nucleotides & Nucleic Acids. Roč. 22, - (2003), s. 329-347. ISSN 1525-7770. E-ISSN 1532-2335
Grant CEP: GA ČR GA203/01/1166; GA AV ČR IAA4055101
Výzkumný záměr: CEZ:AV0Z4055905
Klíčová slova: protection * ŕ-hydroxyphosphonates * oligonucleotides
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 0.813, rok: 2003
In contrast to .I.O./I.-acetyl group, the .I.O./I.-methoxycarbonyl protecting group was found to be excellent non-participating group for the protection of hydroxy function of derivatives of nucleosides at the activation of phosphorus moiety during phosphotriester synthesis of oligonucleotides.
Trvalý link: http://hdl.handle.net/11104/0090481
Počet záznamů: 1