0194566 - UOCHB-X 20020237 RIV US eng J - Článek v odborném periodiku
Snoeck, R. - Holý, Antonín - Dewolf-Peeters, C. - Van Den Oord, J. - De Clercq, E. - Andrei, G.
Antivaccinia activities of acyclic nucleoside phosphonate derivatives in epithelial cells and organotypic cultures.
Antimicrobial Agents and Chemotherapy. Roč. 46, č. 11 (2002), s. 3356-3361. ISSN 0066-4804. E-ISSN 1098-6596
Grant CEP: GA ČR GV203/96/K001
Výzkumný záměr: CEZ:AV0Z4055905
Klíčová slova: phosphonate derivatives
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 4.215, rok: 2002

Series of phosphonate derivatives were tested for their ability to inhibit VV growth. The most active compound was 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-adenine [(S)-HPMPA]. Cidofovir is potentially a good candidate for the treatment of a poxvirus outbreak.
Trvalý link: http://hdl.handle.net/11104/0090241