0194253 - UOCHB-X 20010360 RIV US eng J - Článek v odborném periodiku
Lindsten, K. - Kondrová, Taťána - Konvalinka, Jan - Masucci, M. G. - Dantuma, N. P.
Cell-based fluorescence assay for human immunodeficiency virus type 1 protease activity.
Antimicrobial Agents and Chemotherapy. Roč. 45, č. 9 (2001), s. 2616-2622. ISSN 0066-4804. E-ISSN 1098-6596
Grant CEP: GA ČR GA303/98/1559
Grant ostatní: HHMI(US) 75195-540801; ECTM(XE) ERBFMRXCT960026
Výzkumný záměr: CEZ:AV0Z4055905
Klíčová slova: HIV-1 * protease activity
Kód oboru RIV: CE - Biochemie
Impakt faktor: 4.562, rok: 2001

We developed a new HIV protease assay based on transient expression of artificial protease precursor harboring green fluorescent protein reporter. The assay provides a convenient and noninfectious model for high-throughput screening of substances that can interfere with PR activity in living cells.
Trvalý link: http://hdl.handle.net/11104/0089938