Počet záznamů: 1
Stereoselective synthesis of H-Phe.psi.[CH.sub.2./sub.O]Phe-OH and two HIV-1 protease inhibitors
- 1.0194202 - UOCHB-X 20010289 RIV FR eng C - Konferenční příspěvek (zahraniční konf.)
Mařík, Jan - Hlaváček, Jan
Stereoselective synthesis of H-Phe.psi.[CH2O]Phe-OH and two HIV-1 protease inhibitors.
Peptides 2000. Proceedings of the Twenty-Sixth Europen Peptide Symposium. Paris: Éditions EDK, 2001 - (Martinez, J.; Fehrentz, J.), s. 831-832. ISBN 2-84254-048-4.
[Peptides 2000. European Peptide Symposium /26./. Montpellier (FR), 10.09.2000-15.09.2000]
Výzkumný záměr: CEZ:AV0Z4055905
Klíčová slova: peptide synthesis
Kód oboru RIV: CE - Biochemie
Stereoselective synthesis of selectively protected pseudodipeptide H-Phe.psi.[CH2O]Phe-OH and two HIV-1 protease inhibitors were carried out the introduction of methyleneoxy bond into molecules of HIV protease inhibitors caused the three orders of magnitude dissociation of their inhibitory effect with respect to the presence of either glutamic acid or glutamine residues, respectively.
Trvalý link: http://hdl.handle.net/11104/0089892
Počet záznamů: 1