0193836 - UOCHB-X 20000298 RIV CZ eng J - Článek v odborném periodiku
Janeba, Zlatko - Holý, Antonín - Masojídková, Milena
Synthesis of acyclic nucleoside and nucleotide analogs derived from 6-amino-7.I.H./I.-purine-8(9.I.H./I.)-thione and 8-(methylsulfanyl)adenine.
Collection of Czechoslovak Chemical Communications. Roč. 65, č. 11 (2000), s. 1698-1712. ISSN 0010-0765
Grant CEP: GA ČR GV203/96/K001
Výzkumný záměr: CEZ:AV0Z4055905
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 0.960, rok: 2000

Acyclic nucleotide analogs derived from 6-amino-7H-purine-8(9H)-thione and 8-(methylsulfanyl)adenine were prepared by modification of starting 8-bromoadenines. Alkylation of 6-amino-7H-purine-8(9H)-thione and of 8-(methylsulfanyl)adenine with diverse alkylation agents was studied. 8,3'-S-Anhydro derivatives were also prepared by cyclization of 6-amino-7H-purine-8(9H)-thione derivatives under the Mitsunobu reaction conditions.
Trvalý link: http://hdl.handle.net/11104/0089528