Počet záznamů: 1
Efficient synthesis of 2'-deoxynucleoside 3'-.I.C./I.-phosphonates: reactivity of geminal hydroxyphosphonate moiety
- 1.0193828 - UOCHB-X 20000290 RIV US eng J - Článek v odborném periodiku
Králíková, Šárka - Buděšínský, Miloš - Masojídková, Milena - Rosenberg, Ivan
Efficient synthesis of 2'-deoxynucleoside 3'-.I.C./I.-phosphonates: reactivity of geminal hydroxyphosphonate moiety.
Nucleosides and Nucleotides. Roč. 19, č. 7 (2000), s. 1159-1183. ISSN 0732-8311
Grant CEP: GA MZd NL5441; GA MŠMT LB98233
Grant ostatní: NIH(US) R03TW00673-0
Výzkumný záměr: CEZ:AV0Z4055905
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 0.798, rok: 1999
A simple way for the synthesis of 3'-C-phosphonate derivatives of all four basic 2'-deoxynucleosides is described. The reactivity of the geminal hydroxy phosphonate moiety located at the 3'-carbon atom of the nucleoside was studied with respect to use this type of compounds for the preparation of short oligonucleotides.
Trvalý link: http://hdl.handle.net/11104/0089520
Počet záznamů: 1