0185224 - UJF-V 20010398 RIV DE eng J - Článek v odborném periodiku
Kasalický, J. - Konopková, M. - Melichar, František
The influence of agents depressing lipid metabolism and glukose-insulin on 18-FDG accumulation in myocardium, brain and skeletal muscle in rats.
European Journal of Nuclear Medicine. Roč. 27, č. 8 (2000), s. 1055. ISSN 0340-6997
Výzkumný záměr: CEZ:AV0Z1048901
Kód oboru RIV: BG - Jaderná, atomová a mol. fyzika, urychlovače
Impakt faktor: 3.772, rok: 2000

To evaluate the increase of 18-FDG myocardial concentrationafter administration of antilipemic agents, inducing the shift of lipid to glucose energetic metabolism. The influenceof some agents on 18-FDG uptake in myocardium of rat was compared with changes in brain and skeletal muscle. Highest 18-FDG uptake in intact myocardium could be achieved 45 minutesfollowing 18-FDG injection and by previous dose of antilipemic agent (acipimox). The administration of glucose with insulin had only small effect. In contrast to myocardium lipid- depressing agents caused the decrease of 18-FDG uptake in skeletal muscle. Negligible changes of 18-FDG uptake in brain of rats are probably not appropriate example for that in human brain of a vigilant man.
Trvalý link: http://hdl.handle.net/11104/0081635