Počet záznamů: 1  

MR tracking of stem cells labeled with superparamagnetic nanoparticles in injured CNS

  1. 1. 0173729 - UEM-P 20033050 RIV IT eng J - Článek v odborném periodiku
    Syková, Eva - Jendelová, Pavla - Růžičková, Kateřina - Urdzíková, Lucia - Herynek, V. - Hájek, M.
    MR tracking of stem cells labeled with superparamagnetic nanoparticles in injured CNS.
    International Journal of Artificial Organs. Roč. 26, č. 9 (2003), s. 847 ISSN 0391-3988.
    [World Congress on regenerative Medicine /1./. Lipsko, 22.10.2003-24.10.2003]
    Grant CEP: GA ČR GA304/03/1189; GA MŠk LN00A065
    Výzkumný záměr: CEZ:AV0Z5039906
    Klíčová slova: Stem cells * Nanoparticles
    Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
    Impakt faktor: 0.964, rok: 2003

    Nuclear magnetic resonance (MR) imaging provides a noninvasive method for studying the fate of transplanted cells in vivo. Our study demonstrates that grafted MSC and ESC migrate into an injured CNS, where only a small portion differentiated to neurons and astrocytes. The contrast agent, based on iron-oxide nanoparticles, can be used as a marker for long-term noninvasive MR tracking of implanted stem cells.
    Trvalý link: http://hdl.handle.net/11104/0070755