0173582 - UEM-P 20023027 RIV US eng J - Článek v odborném periodiku
Iben, S. - Tschochner, H. - Bier, M. - Hoogstraten, D. - Hozák, Pavel - Egly, J. M. - Grummt, I.
TFIIH Plays an Esswntial Role in RNA Polymerase I Transcription.
Cell. Roč. 109, č. 3 (2002), s. 297-306. ISSN 0092-8674. E-ISSN 1097-4172
Grant CEP: GA AV ČR IAA5039202
Výzkumný záměr: CEZ:AV0Z5039906
Klíčová slova: mouse * yeast
Kód oboru RIV: EA - Morfologické obory a cytologie
Impakt faktor: 27.254, rok: 2002

TFIIH is a multisubunit protein complex that plays an essential role in nucleotide excision repair and transcription of protein-coding genes. Here, we report that TFIIH is also required for ribosomal RNA synthesis in vivo and in vitro. The results provide a molecular link between RNA polymerase I transcription and transcription-coupled repair of active ribosomal RNA genes.
Trvalý link: http://hdl.handle.net/11104/0070613