0142473 - FGU-C 20030087 RIV NL eng J - Článek v odborném periodiku
Manetto, G. - Silvana Bellini, M. - Deyl, Zdeněk
Application of capillaries with minimized electroosmotic flow to the electrokinetic study of acidic drug-beta-oleoyl-gamma-palmitoyl-L-alpha-phosphatidyl choline liposome interactions.
Journal of Chromatography A. Roč. 990, 1-2 (2003), s. 205-214. ISSN 0021-9673. E-ISSN 1873-3778
Výzkumný záměr: CEZ:AV0Z5011922
Klíčová slova: liposomes * capillary electrophoresis
Kód oboru RIV: CB - Analytická chemie, separace
Impakt faktor: 2.922, rok: 2003

Interaction of a model set of common drug varying widely in their polarity as well as in their chemical structure with liposomes was investigated by means of capillary electrophoresis. The liposomes showed practically no electrophoretic mobility and formed a stable plug in the capilary. Separation resulted in two regions in the electropherogram, namely that which contained the unbound species and that corresponding to the liposome (lipid)-bound fraction.
Trvalý link: http://hdl.handle.net/11104/0040176