0142320 - FGU-C 20020043 RIV US eng J - Článek v odborném periodiku
Šťastný, František - Schwendt, M. - Lisý, Václav - Ježová, D.
Main subunits of ionotropic glutamate receptors are expressed in isolated rat brain microvessels.
Neurological Research. Roč. 24, č. 1 (2002), s. 93-96. ISSN 0161-6412. E-ISSN 1743-1328
Grant CEP: GA ČR GA305/99/1317; GA ČR GA309/99/0211
Grant ostatní: VEGA(SK) 2/6084
Výzkumný záměr: CEZ:AV0Z5011922
Klíčová slova: Glutamate receptor * gene expression and binding * blood-brain barrier
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 0.969, rok: 2002

The results confirmed the presence of both NMDAR1 and GLUR1 mRNAs in microvessels of seven brain regions. Speci-fic bindings of [3H]Glu to capillary membranes displaceable by AMPA, NMDA and mGluR agonists were observed. Thus, the rat brain capillaries and/or the adhering astrocyte pro-cesses possess functional glutamate receptors.
Trvalý link: http://hdl.handle.net/11104/0040026