0142196 - FGU-C 20010251 RIV IE eng J - Článek v odborném periodiku
Stuchlík, Aleš - Kubová, Hana - Mareš, Pavel
Single systemic dose of vigabatrin induces early proconvulsant and later anticonvulsant effect in rats.
Neuroscience Letters. Roč. 312, č. 1 (2001), s. 37-40. ISSN 0304-3940. E-ISSN 1872-7972
Výzkumný záměr: CEZ:AV0Z5011922
Klíčová slova: epilepsy * vigabatrin * electroencephalograph afterdischarges
Kód oboru RIV: ED - Fyziologie
Impakt faktor: 2.021, rok: 2001

A biphasic antiepileptic effect of vigabatrin was demonstated in adult rats with chronic implanted electrodes.The initial proconvulsant effect might be due to a different onset of VGB action in individual brain structures, but an additional mechanism of action cannot be excluded.
Trvalý link: http://hdl.handle.net/11104/0039903