Počet záznamů: 1
Effect of Selected Stilbenoids on Human Fecal Microbiota
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SYSNO ASEP 0503660 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Effect of Selected Stilbenoids on Human Fecal Microbiota Tvůrce(i) Jaimes, J. D. (CZ)
Jarošová, V. (CZ)
Veselý, O. (CZ)
Mekadim, Chahrazed (UZFG-Y) ORCID
Mrázek, Jakub (UZFG-Y) RID, ORCID
Maršík, P. (CZ)
Killer, Jiří (UZFG-Y) RID, ORCID
Smejkal, K. (CZ)
Klouček, P. (CZ)
Havlík, J. (CZ)Číslo článku 744 Zdroj.dok. Molecules. - : MDPI
Roč. 24, č. 4 (2019)Poč.str. 25 s. Forma vydání Online - E Jazyk dok. eng - angličtina Země vyd. CH - Švýcarsko Klíč. slova phenolics ; polyphenols ; stilbenoids Vědní obor RIV EE - Mikrobiologie, virologie Obor OECD Microbiology CEP GA16-07193S GA ČR - Grantová agentura ČR Způsob publikování Open access Institucionální podpora UZFG-Y - RVO:67985904 UT WOS 000460805900090 EID SCOPUS 85061926943 DOI 10.3390/molecules24040744 Anotace Dietary phenolics or polyphenols are mostly metabolized by the human gut microbiota. These metabolites appear to confer the beneficial health effects attributed to phenolics. Microbial composition affects the type of metabolites produced. Reciprocally, phenolics modulate microbial composition. Understanding this relationship could be used to positively impact health by phenolic supplementation and thus create favorable colonic conditions. This study explored the effect of six stilbenoids (batatasin III, oxyresveratrol, piceatannol, pinostilbene, resveratrol, thunalbene) on the gut microbiota composition. Stilbenoids were anaerobically fermented with fecal bacteria from four donors, samples were collected at 0 and 24 h, and effects on the microbiota were assessed by 16S rRNA gene sequencing. Statistical tests identified affected microbes at three taxonomic levels. Observed microbial composition modulation by stilbenoids included a decrease in the Firmicutes to Bacteroidetes ratio, a decrease in the relative abundance of strains from the genus Clostridium, and effects on the family Lachnospiraceae. A frequently observed effect was a further decrease of the relative abundance when compared to the control. An opposite effect to the control was observed for Faecalibacterium prausnitzii, whose relative abundance increased. Observed effects were more frequently attributed to resveratrol and piceatannol, followed by thunalbene and batatasin III. Pracoviště Ústav živočišné fyziologie a genetiky Kontakt Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554 Rok sběru 2020 Elektronická adresa https://doi.org/10.3390/molecules24040744
Počet záznamů: 1